Quantitative studies indicate that the rhizome contains fatty oil, protein, carbohydrates, crude fiber, ash, vitamins, minerals, water, and volatile oil The non-volatile pungent phytochemicals of ginger consists of gingerols, shogaols, paradols, and zingerone Due to the presence of a -hydroxy keto group, gingerols are highly thermolabile and readily undergo dehydration to form the corresponding shogaols. The basis of the derived systemic DNELs for geranyl acetate formed the available repeated dose toxicity studies with food-grade geranyl acetate (71% geranyl acetate (CAS 105-87-3) and 29% citronellyl acetate (CAS 150-84-5)) in a weight of evidence performed by the National Toxicity Program of the US National Institutes of Health (NTP, 1987).
Classification (67/548/EEC, 1999/45/EC) Rose, metallic, citronella, pear, mushroom notesweet fruity-floral rose lavender Sweet fruity-floral rosy somewhat greenCitronella, Floral, Fruity, Green, Metallic/ Metal, MushroomSweet fruity-floral, rosy with some green undertones Its condensed liquid has a sightly yellow color. In an oral 90 day repeated dose toxicity study in B6C3F1mice, mortalities, delays in body weight gain, cytoplasmic vacuolization with lipid inclusions indicative of fatty degeneration in liver, kidney and myocardium and stomach lesions including inflammation and edema were reported. Excludes regulated items and items that ship on ice. Please check that the Product Number you have entered is correct. If your information is correct and you are still not able to view the requested SDS, /LABORATORY ANIMALS: Acute Exposure/ Groups of 5 male and female F344/N rats and B6C3F1 mice were administered a single dose of food-grade geranyl acetate (500, 1,000, 2,000, 4,000, or 8,000 mg/kg bw) in corn oil by gavage. The quantity of production in the world in 2006 is estimated to be 5 000 000 kl. Therefore, it is not surprising that various investigators have found that yeasts are the primary spoilage microorganisms for yogurt and that fruits, flavors, and coloring agents are frequent contamination sources.
A toxicity reference value (TRV) is a toxicological index that, when compared with exposure, is used to qualify or quantify a risk to human health. Applying all assessment factors, the dermal long-term systemic DNEL derived was Based on the limited data on dermal penetration no high dermal penetration potential is assumed and therefore a twofold higher oral absorption is considered appropriate.Assessment factor for allometric scaling according to R8 ECHA 2008Substance specific assessment factor: Major adverse effects observed were predominantly general systemic toxicity.On the basis of these findings, no toxicodynamic and/or additional toxicokinetic differences between test animals and humans is to be expected besides aspects already covered by allometric scaling.Some organ specific adverse effects (e.g. The antimicrobial action of geraniol has previously been demonstrated against a number of bacterial and fungal species, with Dunlop et al. By continuing on our website, you accept the use of cookies. This site is not fully supported in Internet Explorer 7 (and earlier versions).
Therefore a NOAEL of 710 mg/kg bw/d from the 90 day study in mice and the 2 year study in rats has been been taken as point of departure for the respective DNELs. Rose, metallic, citronella, pear, mushroom noteUse: RECOMMENDED USES: Fine fragrance, personal care, fabric care, home care.Flavor: fruity, orange, lemon, mandarin, grapefruitOdor: sweet fruity-floral rose lavender Sweet fruity-floral rosy somewhat greenUse: Used in floral and citrus-type perfumes and in various fruit flavor compositions.Odor: Sweet, fruity-floral, rosy, somewhat green and remotely Lavender-likeUse: Widely used in floral, fruity, herbaceous, and citrus fragrances. On the basis of the low vapour pressure, the exposure with geranyl acetate via inhalation as a vapour is low. It is worth noting that (1 R,3 R,4 S)-(−)-menthol was able to amplify the pain threshold, while (+)-menthol did not exhibit any analgesic effects Menthol and limonene have been considered the most effective transdermal penetration enhancers, significantly increasing the transdermal delivery of certain drugs such as caffeine and hydrocortisone. A mixture of TAGs and a stoicheometric amount of methanol includes micelles of methanol because the solubility is only half a mole of TAGs. Geranyl acetate is a natural organic compound that is classified as a monoterpene.It is a colorless liquid with a pleasant floral or fruity rose aroma. It was observed that the addition of the appropriate concentration of the essential oil (0.1%, w/v) improved the physicochemical properties as well as sensory characteristics of yogurt, and this essential oil could be used for decontamination of dairy products such as yogurt from mycotoxigenic fungi and prevent mycotoxins formation, in addition to its beneficial properties as a functional food.Phytochemical studies have shown that the ginger rhizome contains a wide variety of biologically active compounds. However, the chosen NOAEL as point of departure also includes these species specific effects. lipidosis) were found to be species specific. Chronic aquatic toxicity, Category 2 H411: Toxic to aquatic life with long lasting effects. Constit.