This bacterium can synthesize struvite stones (because of its strong urease activity) and develop encrusted pyelitis and cystitis [2–4].

%%EOF endstream endobj 75 0 obj < It is a slow‐growing, lipophilic, asaccharolytic and usually multidrug‐resistant organism with potent urease activity. Most often, these reports are false positives.

The DtxR-iron complex then binds to the diphtheria toxin gene operator, repressing synthesis of toxin.Corynebacteria are taxonomically related to the mycobacteria and Although other virulence factors exist, the most significant virulence factor is diphtheria toxin, a 58-kDa protein produced by strains carrying β-corynebacteriophage.

Corynebacterium urealyticum is a lipophilic species that characteristically expresses multidrug resistance and is a urease producer.

Experienced personnel, however, are able to identify elements in urine sediment whether it is stained or not, and some prefer to examine unstained urine sediment under low illumination.A: Not if you hope to identify delicate sediment elements such as cellular casts, because the force generated for centrifuging blood is very high and will disrupt cellular casts. The correlation between API and MALDI-TOF results was 89%.

Hint: the test results included a positive urea. Identification and characterization of smallest pore-forming protein in the cell wall of pathogenic Corynebacterium urealyticum DSM 7109. Species identification recommended for any isolate thought to be causing human infection.

Corynebacterium urealyticum.



The time elapsed from the endoscopic intervention to the occurrence of the disease is variable, ranging from several days to several years (From a clinical point of view, encrusted cystitis is characterized by the same symptoms as the other forms of cystitis, associated with the inconstant elimination of calcified detritus. Infections outside the urinary tract occur at any age, predominantly also in males, and more than 50% of the cases occur in patients with urological diseases.
Toxin production is inhibited by iron, which binds to DtxR. Production of diphtheria toxin can be demonstrated in vitro by use of an agar well or antitoxin membrane immunoprecipitin technique (Elek test) or by in vivo toxin neutralization tests in the guinea pig.We use cookies to help provide and enhance our service and tailor content and ads. If you do not receive an email within 10 minutes, your email address may not be registered,

Various bacteria may be found in the urine in specific clinical settings.
Department of Medical Microbiology and Antimicrobial Chemotherapy, Fundación Jiménez Díaz, Madrid, SpainInstitut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universität Bielefeld, Bielefeld, GermanyDepartment of Medical Microbiology and Antimicrobial Chemotherapy, Fundación Jiménez Díaz, Madrid, SpainInstitut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universität Bielefeld, Bielefeld, GermanyUse the link below to share a full-text version of this article with your friends and colleagues.





When administered IV, it can be valuable for treatment of MDR gram-positive bacterial infections, such as methicillin-resistant staphylococcal infections, resistant enterococcal infections, and encrusting cystitis caused by Teicoplanin has a longer half-life and is up to 100 times more lipophilic than vancomycin.



Genitourinary infections (encrusted cystitis) >> bacteremia, endocarditis, wound infections.